What is Pleomorphic Adenoma and Its Affects?

The Pleamorphic adenoma is a term used to describe a tumor which is formed in the salivary gland and is benign in nature in its nascent stages. The tumor which is mostly found in the women and children is also the most common form of adenoma present in the human body which basically includes three components namely epithelial cell component, a stromal (mesenchymal) component and a myoepithelial cell component. These three components are important to recognize the presence of pleomorphic adenoma and this is mainly called the benign mixed tumor.

The pleomorphic adenoma represents the overall 45 to 75% of all the salivary gland neoplasms and the actual incidence annually is 2 to 3.5 reported cases of the 0.1 million people. Though mostly seen in females than in males i.e. in the ratio 2:1, this type of adenoma occurs in people of all ages and usually in the age range of 43-46 years. Of all the salivary glands, the pleomorphic adenoma occurs most commonly in the parotid salivary gland with chances of 70-80% and is less seen in the other parts of the salivary gland.

Initially, it gradually grows as a painless mass which can be present in the gland the same way for years, but the symptoms appear depending on the location. When the tumor first appears in the parotid gland, seldom do the facial nerves appear weak but in the large tumors, this weakness appears to be more due to malignant changes. Normally, patients with small salivary gland tumors show different symptoms like hoarseness, dyspnea, dysphagia, epitaxis, and difficulty in chewing.

People with benign and well circumscribed tumors can easily undergo the surgical resection, however, this pleomorphic adenoma can recur again especially the ones formed in the parotid gland. And the malignant changes occur in 2-7% of the cases where they appear to recur again as deep lobe tumors especially in male gender and in older ages.

The Author is an expert Health adviser and runs a site on pleomorphic adenoma

He is also an editor for Health Encyclopedia

Article Source: http://EzineArticles.com/4079604

Types of Pituitary Adenoma

Pituitary adenoma is commonly found in the benign stages and does not show any symptoms. The pituitary adenomas are found in the epithelial lining of the glandular tissue that forms the pituitary gland in the human brain. It is formed due to mutation in the cells that grow into benign tumors. The tumor is benign in the initial stages when the cells are inactive. But with the progress of time they may become malignant and proliferate to other parts of the body.

In the earlier days, the adenoma was identified using a staining technique where the tumors were exposed to chemicals like haemotoxin and eosin. It was thus named as acidophilic, basophilic and chromophobe. But according to new technology, the acute adenoma is classified based on the type of hormone that is secreted by the tumors. Therefore it could be hormone secreting or chromophobe that does not produce any hormones.

Thus various abnormalities have been identified based on this methodology of classification. A good example is the Cushing's disease that is associated with Corticotrophic adenomas which are a type of pituitary adenoma and they secrete adenosorticotrophic hormone and pro-opiomelocortin hormone.

Acromeagaly is also a genetic abnormality found in gigantic adults as the presence of somatotrophic adenomas that secrete an excessive amount of gonadotrophoic hormone. Several medical conditions are identified by this method of classification of the pituitary adenomas. The said adenomas are present in the benign form, and do not present any symptoms, therefore the adenomas are often identified in the advanced stages, and thus there is a very low survival rate.

The Author is an expert Health adviser and runs a site on pleomorphic adenoma

He is also an editor for Health Encyclopedia

Article Source: http://EzineArticles.com/4062334

Prostate Adenoma

Prostate adenoma is a clinical term for an enlarged prostate. Generally found in older men, prostate adenoma causes the prostate gland to get larger, pressing on the urethra and causing urinary problems and sometimes sexual dysfunction.

There are three stages of prostate adenoma. In the first state, urination frequency increases. Men may need to get up in the middle of the night to urinate. Additionally, the urine stream may be slower, thinner, or weaker than normal.

In stage two, urination becomes more difficult. The urine may dribble out slowly or stop and start instead of coming out in a smooth, constant stream. There may be some straining involved, and the bladder may not empty entirely, causing you to need to go to the bathroom more often. You may need to urinate again just a few minutes after going to the bathroom.

In stage three, the prostate may enlarge so much that urination becomes extremely difficult. The bladder may never empty completely. In rare cases, urination can be blocked completely. This condition is fatal if left untreated.

Prostate problems in men are relatively common. Enlargement is found in most men by the age of 70 or 80.

However, it doesn't always progress to a stage where treatment is critical. If you begin experiencing symptoms of stage two or three prostate adenoma, your doctor will probably want to explore treatment options with you.

Those treatment options may include lifestyle modifications such as reducing alcohol consumption and losing weight, various medications, herbal remedies, or even surgery in advanced cases.

There is some evidence that prostate adenoma may be a warning sign or a precursor to prostate cancer, so your doctor may want to keep an eye on the situation. This may mean frequent examinations to be sure your prostate isn't growing, and that it isn't progressing into a cancerous state.

Looking for information and resources on prostate cancer, infections and problems? Visit: http://www.SymptomsofProstateInfection.com

Article Source: http://EzineArticles.com/5684074